Locked in a pro-inflammatory state

Locked in a pro-inflammatory state

Macrophages absorbing cells infected with viable SARS-CoV-2 particles fail to transition into an anti-inflammatory state, potentially contributing to a damaging immune reaction linked to severe forms of COVID-19.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:eLife 2022-07, Vol.11
Hauptverfasser: Wang Chau, Chiu, Sugimura, Ryohichi
Format: Artikel
Sprache:eng
Schlagworte:
Coronaviruses
COVID-19
Cytokine storm
efferocytosis
Gene expression
Genotype & phenotype
Health aspects
hyperinflammation
Immunology and Inflammation
Inflammation
Insight
macrophage polarization
Macrophages
Medical research
Medicine, Experimental
Pathogens
Proteins
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
tissue repair
Vaccines
Viruses
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Macrophages absorbing cells infected with viable SARS-CoV-2 particles fail to transition into an anti-inflammatory state, potentially contributing to a damaging immune reaction linked to severe forms of COVID-19.
ISSN:2050-084X
2050-084X
DOI:10.7554/eLife.80699