Is lipid accumulation product a better cardiovascular risk predictor in elderly individuals than anthropometric measures?

Population aging is associated with increased prevalence of cardiovascular diseases that have a significant impact on overall morbidity and mortality. Insulin resistance (IR) and visceral obesity are risk factors for vascular damage and cardiometabolic diseases. Estimating the correlation between lipid accumulation product (LAP) and IR in elderly individuals and comparing them to traditional anthropometric indices. Cross-sectional study comprising 411 individuals >60 years, who were treated in a primary care service. Body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), arm circumference (AC), sagittal abdominal diameter (SAD) and waist-hip ratio (WHR) were recorded. IR was estimated based on HOMA-IR (homeostasis model assessment IR index). LAPa index was calculated as [WC-65]×[triglyceride (TG)] in men, and as [WC-58]×[TG] in women, whereas LAPb was calculated by using the minimum WC values recorded for the current sample, i.e., 61.5 cm for women and 71.5 cm for men. There was correlation among LAPa (0.506), LAPb (0.515) and HOMA-IR. LAP was better correlated to HOMA-IR and showed higher area under the curve than BMI, NC, WHR and SAD. Based on the receiver operating characteristic curve analysis, LAPb≥47.40 and LAPa≥52.5 were the best cut-off values used to identify individuals with IR presenting 68.8% and 68.2% sensitivity, and 68.6% and 68.6% specificity, respectively. LAP may be a useful and simple clinical marker to assess cardiometabolic risk factors in the elderly population treated at a primary care service. O envelhecimento da população associa-se ao aumento da prevalência de doenças cardiovasculares, com um impacto significativo na morbimortalidade geral. Resistência à insulina (RI) e obesidade visceral são fatores de risco para lesão vascular e doença cardiometabólica. Estimar a correlação entre produto de acumulação de lípidos (LAP) e IR em indivíduos idosos e compará-los com os índices antropométricos tradicionais. Este estudo transversal incluiu 411 indivíduos acima de 60 anos, atendidos na atenção primária. Foram registradas índice de massa corporal (IMC), circunferência do pescoço (CP), circunferência da cintura (CC), circunferência do quadril (CQ), circunferência do braço (CA), diâmetro abdominal sagital (DAS) e relação cintura-quadril (RCQ). A RI foi estimada pelo HOMA-IR (índice de avaliação do modelo de homeostase). O índice de PALa foi calculado como [WC-65] × [TG] em homens, e [WC-58] × [TG]