Results of a randomized double-blind multicenter clinical trial of the efficacy and safety of riamilovir in the treatment of COVID-19

To evaluate the efficacy and safety of riamilovir in the treatment of COVID-19 in adults. The study included 180 patients with a laboratory-confirmed diagnosis of COVID-19 which fully meet the criteria for inclusion, non-inclusion and exclusion, signed a voluntary informed consent to participate in...

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Veröffentlicht in:Terapevtic̆eskii arhiv 2024-06, Vol.96 (5), p.517-522
Hauptverfasser: Sabitov, A U, Lioznov, D A, Zhdanov, K V, Tikhonova, E P, Esaulenko, E V, Kovtun, O P, Kuznetsov, P L, Sorokin, P V
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Sprache:eng ; rus
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Zusammenfassung:To evaluate the efficacy and safety of riamilovir in the treatment of COVID-19 in adults. The study included 180 patients with a laboratory-confirmed diagnosis of COVID-19 which fully meet the criteria for inclusion, non-inclusion and exclusion, signed a voluntary informed consent to participate in a clinical trial. The efficacy, good tolerability and safety of the drug riamilovir in the treatment of COVID-19 have been established. As a result of a multicenter randomized double-blind clinical trial, the effectiveness of the drug riamilovir for therapeutic use in patients with COVID-19 according to the 1250 mg/day scheme (250 mg capsules 5 times per day) for 10 days was established. The drug riamilovir in a daily dose of 1250 mg for 10 days does not differ in safety from placebo.
ISSN:0040-3660
2309-5342
DOI:10.26442/00403660.2024.05.202770