Lumbar spine abnormalities in patients with obstructive sleep apnoea

Lumbar spine abnormalities in patients with obstructive sleep apnoea

Previous studies suggested cervical spondylosis as a risk factor for development of obstructive sleep apnoea (OSA). We aimed to assess lumbar disc degeneration in patients with OSA and correlate the findings with symptoms and disease severity. Twenty-seven patients with OSA and 29 non-OSA controls u...

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Veröffentlicht in:Scientific reports 2021-08, Vol.11 (1), p.16233-16233, Article 16233
Hauptverfasser: Tarnoki, Adam Domonkos, Tarnoki, David Laszlo, Oláh, Csaba, Szily, Marcell, Kovacs, Daniel T., Dienes, András, Piroska, Marton, Forgo, Bianka, Pinheiro, Marina, Ferreira, Paulo, Kostyál, László, Meszaros, Martina, Pako, Judit, Kunos, Laszlo, Bikov, Andras
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Sprache:eng
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Apnea
Back pain
Degeneration
Degenerative disc disease
Enzyme-linked immunosorbent assay
Humanities and Social Sciences
Intervertebral discs
Klotho protein
Low back pain
Magnetic resonance imaging
multidisciplinary
Plasma levels
Risk factors
Science
Science (multidisciplinary)
Sleep
Sleep and wakefulness
Sleep apnea
Sleep deprivation
Sleep disorders
Spine
Spine (lumbar)
Spondylosis
Vertebrae
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Beschreibung
Zusammenfassung:Previous studies suggested cervical spondylosis as a risk factor for development of obstructive sleep apnoea (OSA). We aimed to assess lumbar disc degeneration in patients with OSA and correlate the findings with symptoms and disease severity. Twenty-seven patients with OSA and 29 non-OSA controls underwent sleep studies and lumbar magnetic resonance imaging (MRI), and completed the Epworth Sleepiness Scale and the 24-item Roland‐Morris Disability Questionnaire (RMDQ) questionnaires. Plasma klotho was determined with enzyme-linked immunosorbent assay. Patients with OSA had higher number of disc bulges (4.6 ± 3.7 vs. 1.7 ± 2.5, p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-95667-3