Peripheral microvessel area better predicts the severity of coronary stenosis of acute myocardial infarction patients over pulse wave velocity

Microvascular obstruction (MVO) is linked with adverse clinical outcome in acute coronary syndrome (ACS) patients, therefore, early prediction of MVO with non-invasive peripheral microcirculation is crucial in facilitating optimal treatment. Current study aims to analyze the significance of opisthen...

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Veröffentlicht in:Scientific reports 2024-11, Vol.14 (1), p.28584-11, Article 28584
Hauptverfasser: Chen, Chen, Wang, Jing, Huo, Tian Tian, Zhu, Bai Lin, Jin, Xin, Zhao, Zai Hao, Lin, Mei Hua, Liu, Jun Xian, Guo, Zhen Yi, Xu, Wen Hu, Cui, Lan, He, Xiao Nan, Zhang, Yin Hua
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Sprache:eng
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Zusammenfassung:Microvascular obstruction (MVO) is linked with adverse clinical outcome in acute coronary syndrome (ACS) patients, therefore, early prediction of MVO with non-invasive peripheral microcirculation is crucial in facilitating optimal treatment. Current study aims to analyze the significance of opisthenar microvessel area (OMA, measured using optical coherence tomography, OCT) in predicting coronary stenosis (Gensini score, GS) and short-term cardiac recovery of ACS patients and the results were compared to those of arterial stiffness parameters (Pulse Wave Velocity, PWV; Ankle-Brachial Index; ABI). Results showed that cardiac functional parameters (e.g. ejection fraction, EF; fractional shortening, FS) and OMA were higher in normal/low risk (GS 0–≤ 20, n = 69) compared to medium/high risk patients (GS > 20, n = 44, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-79064-0