Q Fever Risk in Patients Treated with Chronic Antitumor Necrosis Factor-Alpha Therapy

Q Fever Risk in Patients Treated with Chronic Antitumor Necrosis Factor-Alpha Therapy

Q fever is a zoonotic bacterial disease caused by Coxiella burnetii. Tumor necrosis factor-alpha (TNF-α) plays a pivotal role in the defense against infection with this Gram-negative coccobacillus. Theoretically, patients who are treated with anti-TNF-α medications are at risk for developing chronic...

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Veröffentlicht in:Case reports in infectious diseases 2016-01, Vol.2016 (2016), p.1-3
Hauptverfasser: Slobodin, Gleb, Boulman, Nina, Kaly, Lisa, Rimar, Doron, Rosner, Itzhak, Elias, Nizar, Odeh, Majed, Astrahan, Anna, Hirsch, Julianna, Rozenbaum, Michael
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Aneurysms
Antigens
Cardiovascular disease
Care and treatment
Case Report
Chronic illnesses
Complications and side effects
Cytomegalovirus
Development and progression
Enzymes
Epidemics
Family medical history
Fever
Gangrene
Health risk assessment
Heart
Immunoglobulins
Infections
Laboratories
Liver
Livestock
Prostheses
Q fever
Tumor necrosis factor inhibitors
Tumor necrosis factor-TNF
Ulcers
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Beschreibung
Zusammenfassung:Q fever is a zoonotic bacterial disease caused by Coxiella burnetii. Tumor necrosis factor-alpha (TNF-α) plays a pivotal role in the defense against infection with this Gram-negative coccobacillus. Theoretically, patients who are treated with anti-TNF-α medications are at risk for developing chronic Q fever. We present two patients who developed Q fever while being treated with anti-TNF-α agents and discuss the significance of timely diagnosis of C. burnetii infection in these patients.
ISSN:2090-6625
2090-6633
DOI:10.1155/2016/4586150