ANÁLISE DE CONTROLE DE DOPING POR ACETAZOLAMIDA UTILIZANDO O SENSOR ELETROQUÍMICO BASEADO NO EPCM-[MnIII/IV(µ-O)(phen)2]2(ClO4)3

The preparation and electrochemical characterization of an electrochemical sensor based on carbon paste electrode modified with [MnIII/IV(µ-O)(phen)2]2(ClO4)3, as well as its application in detection of acetazolamide with interest in doping control analysis are related. The electrochemical behavior of the sensor and the electrooxidation of ACTZ were investigated using the technique of cyclic and linear sweep voltammetry, respectively. The cyclic voltammogram for the electrochemical sensor showed one redox process assigned to MnIII/IV/MnIV/IV couple and electrocatalytic properties in oxidation of ACTZ. The voltammetric response was obtained in a concentration range from 5.00 × 10-7 mol L-1 to 5.00 × 10-6 mol L-1 , being the linear response from 5.00 × 10-7 mol L-1 to 3.50 × 10-6 mol L-1 with limit of quantification 9.90 × 10-5 mol L-1 , limit of detection 2.97 × 10-6 mol L-1 e sensitivity of 39.29 μA L mol-1 .