Infectivity of Norovirus GI and GII from Bottled Mineral Water during a Waterborne Outbreak, Spain

During a waterborne outbreak of norovirus in Spain, we estimated 50% illness doses for a group of exposed (secretor) persons to be 556 (95% CI 319-957) genome copies/day for norovirus GI and 2,934 (95% CI 1,683-5,044) genome copies/day for norovirus GII. Use of a propidium monoazide viability assay...

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Veröffentlicht in:	Emerging infectious diseases 2020-01, Vol.26 (1), p.134-137
Hauptverfasser:	Guix, Susana, Fuentes, Cristina, Pintó, Rosa M, Blanco, Albert, Sabrià, Aurora, Anfruns-Estrada, Eduard, Garrido, Virginia Rodríguez, Alonso, Manuel, Bartolomé, Rosa, Cornejo, Thais, Pumarola, Tomàs, Bosch, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	50% illness dose Adult Antigens Bottled drinking water Caliciviridae Infections - epidemiology Caliciviridae Infections - etiology Caliciviridae Infections - virology Disease Outbreaks Disease susceptibility Diseases Dispatch Estimates Food contamination & poisoning Gastroenteritis Gastroenteritis - epidemiology Gastroenteritis - etiology Gastroenteritis - virology Genes Genetic aspects Genomes Genomics Genotypes GII Health aspects Humans Infection Infections infectivity Infectivity of Norovirus GI and GII from Bottled Mineral Water during Waterborne Outbreak, Spain Medical research Middle Aged Mineral Waters - virology norovirus Norovirus - pathogenicity Spain - epidemiology Viruses Water Waterborne Diseases - epidemiology Waterborne Diseases - virology Waterborne infections
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Zusammenfassung:	During a waterborne outbreak of norovirus in Spain, we estimated 50% illness doses for a group of exposed (secretor) persons to be 556 (95% CI 319-957) genome copies/day for norovirus GI and 2,934 (95% CI 1,683-5,044) genome copies/day for norovirus GII. Use of a propidium monoazide viability assay reduced these values.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2601.190778