Comparison of four routinely used vitamin D automated immunoassays
To compare four automated immunoassays for the measurement of 25(OH)-vitamin D (25-OHD) and to assess the impact on the results obtained from a healthy population. We analysed 100 serum samples on Unicel DxI 800 (Beckman Coulter), Architect i1000 (Abbott), Cobas e411 (Roche) and Liaison XL (DiaSorin...
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Veröffentlicht in: | Journal of medical biochemistry 2021-01, Vol.40 (3), p.277-285 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To compare four automated immunoassays for the measurement of 25(OH)-vitamin D (25-OHD) and to assess the impact on the results obtained from a healthy population.
We analysed 100 serum samples on Unicel DxI 800 (Beckman Coulter), Architect i1000 (Abbott), Cobas e411 (Roche) and Liaison XL (DiaSorin). Passing-Bablok regression and Bland-Altman plots were used for method comparison. In order to categorise the obtained values, results were categorised into the following groups: 0-25 nmol/L, 25-50 nmol/L, 50-75 nmol/L and above 75 nmol/L and compared. The percentage of samples below 75 nmol/L, and below 50 nmol/L was then calculated for every method.
According to paired comparisons, each method differs from others (p |
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ISSN: | 1452-8258 1452-8266 |
DOI: | 10.5937/jomb0-27531 |