First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil

Carbapenemase-resistant enterobacteria that produce the bla NDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil. The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene se...

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Veröffentlicht in:Revista da Sociedade Brasileira de Medicina Tropical 2020, Vol.54, p.e02622020-e02622020
Hauptverfasser: Soares, Cynthia Regina Pedrosa, Oliveira-Júnior, Jorge Belém, Firmo, Elza Ferreira
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Sprache:eng
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Zusammenfassung:Carbapenemase-resistant enterobacteria that produce the bla NDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil. The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes. The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected. The current report of the blaNDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.
ISSN:0037-8682
1678-9849
1678-9849
DOI:10.1590/0037-8682-0262-2020