Anticancer Potential of Resveratrol, beta-Lapachone and Their Analogues

Anticancer Potential of Resveratrol, beta-Lapachone and Their Analogues

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2020-02, Vol.25 (4), p.893, Article 893
Hauptverfasser: Ferraz da Costa, Danielly C., Rangel, Luciana Pereira, Duarte da Cunha Martins-Dinis, Mafalda Maria, da Silva Ferretti, Giulia Diniz, Ferreira, Vitor F., Silva, Jerson L.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry & Molecular Biology
cancer
Chemistry
Chemistry, Multidisciplinary
Life Sciences & Biomedicine
Physical Sciences
resveratrol
Review
Science & Technology
β-lapachone
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Beschreibung
Zusammenfassung:This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules25040893