Extreme βHCG levels in first trimester screening are risk factors for adverse maternal and fetal outcomes

Extreme βHCG levels in first trimester screening are risk factors for adverse maternal and fetal outcomes

Multiples of the normal median (MoM) of free βHCG is a valuable parameter in evaluation of risk of adverse pregnancy outcomes. In the current retrospective study, we assessed the maternal and fetal outcomes in pregnant women having free βHCG MoM levels  5 in their first trimester screening (FTS). Re...

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Veröffentlicht in:Scientific reports 2023-01, Vol.13 (1), p.1228-1228, Article 1228
Hauptverfasser: Younesi, Sarang, Eslamian, Laleh, Khalafi, Nikta, Taheri Amin, Mohammad Mahdi, Saadati, Pourandokht, Jamali, Soudabeh, Balvayeh, Payam, Modarressi, Mohammad-Hossein, Savad, Shahram, Amidi, Saloomeh, Delshad, Saeed, Navidpour, Fariba, Yazdani, Bahareh, Aasdi, Fatemeh, Chagheri, Samira, Mohammadi, Yalda, Marsoosi, Vajiheh, Jamal, Ashraf, Ghafouri-Fard, Soudeh
Format: Artikel
Sprache:eng
Schlagworte:
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Biomarkers
Birth weight
Chorionic Gonadotropin, beta Subunit, Human
Chromosome aberrations
Diabetes mellitus
Edema
Female
Fetuses
Gestational age
Gestational diabetes
Humanities and Social Sciences
Humans
Hydrops fetalis
Hypertension
Infant, Newborn
Laboratories
Low birth weight
multidisciplinary
Obstetrics
Pre-eclampsia
Preeclampsia
Pregnancy
Pregnancy complications
Pregnancy Trimester, First
Respiratory distress syndrome
Retrospective Studies
Risk Factors
Science
Science (multidisciplinary)
Trisomy
Turner's syndrome
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Zusammenfassung:Multiples of the normal median (MoM) of free βHCG is a valuable parameter in evaluation of risk of adverse pregnancy outcomes. In the current retrospective study, we assessed the maternal and fetal outcomes in pregnant women having free βHCG MoM levels  5 in their first trimester screening (FTS). Relative risk of trisomy 21 was significantly higher in patients having free βHCG MoM > 5. On the other hand, relative risk of trisomies 13 and 18 and Turner syndrome were higher in those having free βHCG MoM 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-28561-9