Establishment of a risk scoring model to predict intraoperative massive hemorrhage in infants with intracranial tumors

Objective To analyze the factors influencing intraoperative massive hemorrhage in infants with intracranial tumors and establish a bleeding risk scoring （BRS） model. Methods Clinical data of 278 infants who underwent elective intracranial tumor resection were retrospectively analyzed. According to the ratio of blood loss （BL） to estimated blood volume （EBV）, all infants were divided into the slight or moderate hemorrhage group （BL/EBV≤0.5） and massive hemorrhage group （BL/EBV > 0.5）. Relevant clinical data and hemorrhage were statistically analyzed. Univariate and multivariate logistic regression analyses were used to identify the independent risk factors for intraoperative massive hemorrhage and establish a BRS model. Forty-five infants undergoing intracranial tumor resection were recruited in this study. The receiver operating characteristic （ROC） curve was delineated to evaluate the performance of this model. Results One hundred and eighty-three infants were assigned into in the slight or moderate hemorrha