First-phase ejection fraction: association with remodelling and outcome in aortic valve stenosis

First-phase ejection fraction: association with remodelling and outcome in aortic valve stenosis

BackgroundFirst-phase ejection fraction (EF1), the left ventricular (LV) ejection fraction (EF) until the time of peak transaortic velocity, is a novel marker of subclinical LV dysfunction able to predict adverse events in aortic stenosis (AS). This study investigated the association between end-sys...

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Veröffentlicht in:Open heart 2021-02, Vol.8 (1), p.e001543
Hauptverfasser: Carter-Storch, Rasmus, Mogensen, Nils Sofus Borg, Christensen, Nicolaj Lyhne, Ali, Mulham, Laursen, Kristian Bach, Pellikka, Patricia A, Moller, Jacob Eifer, Dahl, Jordi S
Format: Artikel
Sprache:eng
Schlagworte:
aortic valve stenosis
Asymptomatic
Cardiac arrhythmia
echocardiography
Ejection fraction
Heart attacks
magnetic resonance imaging
Patients
Valvular Heart Disease
Velocity
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Zusammenfassung:BackgroundFirst-phase ejection fraction (EF1), the left ventricular (LV) ejection fraction (EF) until the time of peak transaortic velocity, is a novel marker of subclinical LV dysfunction able to predict adverse events in aortic stenosis (AS). This study investigated the association between end-systolic wall stress (ESWS) and EF1 in severe AS, as well as the prognostic value of EF1 in severe asymptomatic AS.MethodsTwo prospectively gathered cohorts of 94 asymptomatic patients and 108 symptomatic patients scheduled for aortic valve replacement (AVR), all with severe AS (aortic valve area
ISSN:2053-3624
2398-595X
2053-3624
DOI:10.1136/openhrt-2020-001543