Comparative Evaluation of Different Antioxidants on Reversal of Microtensile Bond Strength of Composite Resin in Endodontically Treated Tooth Surface

Introduction: The use of Sodium Hypochlorite (NaOCl) as an endodontic irrigant changes the properties of dentine and lowers the bond strength of resin cements to dentine. But it can be reversed by the use of antioxidants. Aim: To evaluate the effect of different antioxidants for restoring adhesion potential/reversal of microtensile bond strength of dentin of the pulp chamber treated with NaOCl and Ethylenediaminetetracetic Acid (EDTA). Materials and Methods: It was a laboratory based experimentalin-vitro study in which 40 freshly extracted human incisors were selected and cut to expose the pulp chamber dentin. The specimens were distributed into five groups: Group I samples were irrigated with 5.25% NaOCl for 30 minutes followed by 17% EDTA for 3 minutes and final rinse was done with 5.25% NaOCl (Positive control). Group II samples were treated with distilled water only (Negative control). In Group III, samples were treated same as in group I followed by 10% Sodium Ascorbate (SA) for 10 minute. Samples of group IV samples were also treated as in group I followed by application of 5% solution of Alpha tocopherol with for 10 minutes. Group V samples were treated same as in group I followed by rinse with 5% solution of Sodium Thiosulphate (Na2S2O3) for 10 minutes. Composite resin build up was performed and interface was tested by using Universal testing machine for Microtensile bond strength. The resulting data was analysed by one-way Analysis of Variance (ANOVA) and Mann-Whitney U test (p