Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation

Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation

In order to evaluate whether retroelements could be active in the psoriatic lesion, we 1/quantified endogenous reverse transcriptase (RT) activity, 2/localised RT-expressing cells 3/evaluated the effects of RT inhibitors on keratinocyte proliferation and differentiation in a skin culture model.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Retrovirology 2009-09, Vol.6 (S2), p.P60-P60, Article P60
Hauptverfasser: Molès, Jean-Pierre, Tesniere, Anne, Dumas, Marc, Bonté, Frédéric, Guilhou, J-J
Format: Artikel
Sprache:eng
Schlagworte:
Genomes
Medical research
Poster Presentation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In order to evaluate whether retroelements could be active in the psoriatic lesion, we 1/quantified endogenous reverse transcriptase (RT) activity, 2/localised RT-expressing cells 3/evaluated the effects of RT inhibitors on keratinocyte proliferation and differentiation in a skin culture model.
ISSN:1742-4690
1742-4690
DOI:10.1186/1742-4690-6-S2-P60