Myeloperoxidase and its negative relationship with cholesterol efflux capacity in patients with psoriasis: results from an observational cohort study

Dear Editor Inflammation and oxidative stress can lower the functionality of apolipoprotein A-1 (ApoA1) and high-density lipoprotein (HDL) molecules, leading to defective reverse cholesterol transport and accelerating early atherosclerosis [1]. [...]a link between MPO levels and cholesterol efflux in human psoriasis has not been previously investigated. [...]the aim of this study was to evaluate the relationship between MPO concentration and RCT in a cohort of chronically inflamed psoriasis patients. SEE PDF] Similarly, between the two groups, we found no significant difference in HDL or LDL cholesterol, particle number and size, or triglyceride concentration (Table 1).