Successful Hematopoietic Stem Cell Transplantation from a Matched Related Donor with Beta-Thalassemia Minor for Severe Aplastic Anemia

Successful Hematopoietic Stem Cell Transplantation from a Matched Related Donor with Beta-Thalassemia Minor for Severe Aplastic Anemia

The first-line treatment for severe aplastic anemia (SAA) patients is hematopoietic stem cell transplantation (HSCT), with full-matched related donors considered the most suitable. We report a case of SAA in which the patient successfully underwent HSCT from a donor with β-thalassemia minor. The pat...

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Veröffentlicht in:Children (Basel) 2020-10, Vol.7 (10), p.162
Hauptverfasser: Jung, Mi Young, Lim, Young Tae, Lim, Hyunji, Hah, Jeong Ok, Lee, Jae Min
Format: Artikel
Sprache:eng
Schlagworte:
aplastic anemia
beta-thalassemia
Case Report
hematopoietic stem cell transplantation
thalassemia minor
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Zusammenfassung:The first-line treatment for severe aplastic anemia (SAA) patients is hematopoietic stem cell transplantation (HSCT), with full-matched related donors considered the most suitable. We report a case of SAA in which the patient successfully underwent HSCT from a donor with β-thalassemia minor. The patient in this case underwent HSCT from a human leukocyte antigen (HLA)-matched younger brother with β-thalassemia minor. A 7-year-old girl was referred to our facility following a 6-month history of easy bruising and pallor. Laboratory examinations showed pancytopenia and hypocellular bone marrow with cellularity of
ISSN:2227-9067
2227-9067
DOI:10.3390/children7100162