Altered extracellular matrix correlates with an immunosuppressive tumor microenvironment and disease progression in younger adults with oral cavity squamous cell carcinoma

Oral cavity squamous cell carcinoma (OSCC) occurs most frequently in patients >60 years old with a history of tobacco and alcohol use. Epidemiological studies describe increased incidence of OSCC in younger adults (

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Veröffentlicht in:	Frontiers in oncology 2024-06, Vol.14, p.1412212
Hauptverfasser:	Estephan, Leonard E, Kumar, Gaurav, Stewart, Matthew, Banoub, Raphael, Linnenbach, Alban, Harshyne, Larry A, Martinez-Outschoorn, Ubaldo E, Mahoney, My G, Curry, Joseph M, Johnson, Jennifer, South, Andrew P, Luginbuhl, Adam J
Format:	Artikel
Sprache:	eng
Schlagworte:	age-related tumor aggressiveness extracellular matrix immunosuppression Oncology oral cavity squamous cell carcinoma (OSCC) tumor microenvironment
Online-Zugang:	Volltext
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Zusammenfassung:	Oral cavity squamous cell carcinoma (OSCC) occurs most frequently in patients >60 years old with a history of tobacco and alcohol use. Epidemiological studies describe increased incidence of OSCC in younger adults (
ISSN:	2234-943X 2234-943X
DOI:	10.3389/fonc.2024.1412212