Combination of Atrial Fibrillation and Coronary Heart Disease in Patients in Clinical Practice: Comorbidities, Pharmacotherapy and Outcomes (Data from the REСVASA Registries)

Aim. Assess the structure of comorbid conditions, cardiovascular pharmacotherapy and outcomes in patients with atrial fibrillation (AF) and concomitant coronary artery disease (CAD) included in the outpatient and hospital RECVASA registries. Materials and methods . 3169 patients with AF were enrolle...

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Veröffentlicht in:Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii 2021-01, Vol.17 (5), p.702-711
Hauptverfasser: Loukianov, M. M., Martsevich, S. Yu, Andrenko, E. Yu, Yakushin, S. S., Vorobiev, A. N., Pereverzeva, K. G., Zagrebelny, A. V., Okshina, Е. Yu, Yakusevich, V. V., Yakusevich, Vl. Vl, Pozdnyakova, E. M., Gomova, T. A., Fedotova, E. E., Valiakhmetov, M. M., Mikhin, V. P., Maslennikova, Yu. V., Belova, E. N., Klyashtorny, V. G., Kudryashov, E. V., Makoveeva, A. N., Tatsii, Ju. E., Boytsov, S. A., Drapkina, O. M.
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Zusammenfassung:Aim. Assess the structure of comorbid conditions, cardiovascular pharmacotherapy and outcomes in patients with atrial fibrillation (AF) and concomitant coronary artery disease (CAD) included in the outpatient and hospital RECVASA registries. Materials and methods . 3169 patients with AF were enrolled in outpatient RECVASA (Ryazan), RECVASA AF-Yaroslavl registries and hospital RECVASA AF (Moscow, Kursk, Tula). 2497 (78.8%) registries of patients with AF had CAD and 703 (28.2%) of them had a previous myocardial infarction (MI). Results. There were 2,497 patients with a combination of AF and CAD (age was 72.2±9.9 years; 43.1% of men; CHA2DS2-VASc – 4.57±1.61 points; HAS-BLED – 1.60±0,75 points), and the group with AF without CAD included 672 patients (age was 66.0±12.3 years; 43.2% of men; CHA2DS2-VASc – 3.26±1.67 points; HAS-BLED – 1,11±0.74 points). Patients with CAD were on average 6.2 years older and had a higher risk of thromboembolic and hemorrhagic complications (p
ISSN:1819-6446
2225-3653
DOI:10.20996/1819-6446-2021-10-03