Acute Respiratory Distress Syndrome; A Review of Recent Updates and a Glance into the Future

Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains s...

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Veröffentlicht in:Diagnostics (Basel) 2023-04, Vol.13 (9), p.1528
Hauptverfasser: Ramji, Husayn F, Hafiz, Maida, Altaq, Hiba Hammad, Hussain, Syed Talal, Chaudry, Fawad
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Sprache:eng
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Zusammenfassung:Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory failure that accounts for 10% of admissions to the ICU and is associated with approximately 40% mortality in severe cases. Despite significant mortality and healthcare burden, the mainstay of management remains supportive care. The recent pandemic of SARS-CoV-2 has re-ignited a worldwide interest in exploring the pathophysiology of ARDS, looking for innovative ideas to treat this disease. Recently, many trials have been published utilizing different pharmacotherapy targets; however, the long-term benefits of these agents remain unknown. Metabolomics profiling and stem cell transplantation offer strong enthusiasm and may completely change the outlook of ARDS management in the near future.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics13091528