Pd/C-mediated synthesis of indoles in water

Pd/C-mediated synthesis of indoles in water

We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Beilstein journal of organic chemistry 2009-09, Vol.5 (1), p.46-46
Hauptverfasser: Layek, Mohosin, Lakshmi, Udaya, Kalita, Dipak, Barange, Deepak Kumar, Islam, Aminul, Mukkanti, K, Pal, Manojit
Format: Artikel
Sprache:eng
Schlagworte:
charcoal
Chemistry
copper
C–C bond
Full Research Paper
indoles
palladium
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the Pd/C-mediated coupling reaction.
ISSN:1860-5397
1860-5397
DOI:10.3762/bjoc.5.46