A review of Spinosyns, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests

Spinosyns are a class of insecticides with a broad range of action against many insect pests belonging to different orders, noxious to a wide variety of agricultural crops; spinosyns were also used against insects of sanitary interest. Spinosyns are derivative of biological active substances produced by soil Actinomycete Saccharopolyspora spinosa; being of biological origin, they are considered to have a low environmental impact and they are not much aggressive against nontarget species. They act as allosteric activators of nicotinic acetylcholine receptors; thanks to their mode of action the resistance phenomena are uncommon, even few cases of resistance were recently reported. For all these reasons at present they are one of the most interesting product to be used in fighting against agriculture pests.