Diagnostic and prognostic role of nitroglycerin-induced dilation in patients with suspected vasospastic angina, combined with ergonovine provocation test

The diagnostic and prognostic role of nitroglycerin-induced dilation (NID) combined with ergonovine provocation test in patients with suspected VSA patients is not clear. A total of 438 consecutive patients who underwent the ergonovine provocation test for the diagnosis of vasospastic angina (VSA) w...

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Veröffentlicht in:	Scientific reports 2021-12, Vol.11 (1), p.23834-23834, Article 23834
Hauptverfasser:	Kim, Minsu, Jang, Albert Youngwoo, Oh, Pyung Chun, Suh, Soon Yong, Lee, Kyounghoon, Kang, Woong Chol, Ahn, Taehoon, Han, Seung Hwan
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4019 692/699/75 Aged Angina Angina pectoris Angina Pectoris - diagnosis Angina Pectoris - etiology Coronary Vasospasm - complications Coronary Vasospasm - diagnosis Coronary Vessels - drug effects Diagnosis Ergonovine - administration & dosage Ergonovine - toxicity Female Heart Function Tests - methods Heart Function Tests - standards Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Nitroglycerin Nitroglycerin - administration & dosage Nitroglycerin - pharmacology Oxytocics - administration & dosage Oxytocics - toxicity Patients Science Science (multidisciplinary) Sensitivity and Specificity Vasodilator Agents - administration & dosage Vasodilator Agents - pharmacology
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Zusammenfassung:	The diagnostic and prognostic role of nitroglycerin-induced dilation (NID) combined with ergonovine provocation test in patients with suspected VSA patients is not clear. A total of 438 consecutive patients who underwent the ergonovine provocation test for the diagnosis of vasospastic angina (VSA) were enrolled. Patients with VSA (n = 52) had a significantly greater coronary response to ergonovine (− 84.3 ± 10.5% vs. − 38.4 ± 17.9%, p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-03338-0