Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual

Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual

Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, a...

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Veröffentlicht in:Stem cell research 2020-05, Vol.45, p.101809-101809, Article 101809
Hauptverfasser: Zhang, Jiwei, Wei, Liting, Wang, Rui, Li, Xunhua, Liu, Zhangsuo
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Cell Differentiation
Cell Line
Cellular Reprogramming
Humans
Induced Pluripotent Stem Cells
Male
Pluripotent Stem Cells
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Zusammenfassung:Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, and maintained the normal karyotype. This cell line can be used as a control line for disease modelling.
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2020.101809