Association between intrahepatic triglyceride content in subjects with metabolically healthy abdominal obesity and risks of pre-diabetes plus diabetes: an observational study

ObjectiveWe aimed to evaluate the association of intrahepatic triglyceride (IHTG) content in subjects with metabolically healthy abdominal obesity (MHAO) on risks of pre-diabetes plus diabetes.DesignCross-sectional survey.SettingLianqian community, the First Affiliated Hospital of Xiamen University,...

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Veröffentlicht in:	BMJ open 2022-02, Vol.12 (2), p.e057820-e057820
Hauptverfasser:	Xu, Qiaoyan, Zhang, Junfeng, Han, Haiwei, Chen, Ning, Lai, Fangfang, Liu, Yongwen, Huang, Caoxin, Lin, Mingzhu, Zhang, Wei, Wang, Shunqin, Liu, Changqin, Li, Zhibin
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adult adult gastroenterology Body mass index Cardiovascular disease Cholesterol Cross-Sectional Studies Diabetes Diabetes and Endocrinology Fatty acids general diabetes Glucose Hemoglobin Hepatitis hepatology High density lipoprotein Humans Liver Liver diseases Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - epidemiology Obesity Obesity - complications Obesity, Abdominal - complications Obesity, Abdominal - epidemiology Obesity, Metabolically Benign - complications Observational studies Plasma Prediabetic State - complications Prediabetic State - epidemiology Spectrum analysis Triglycerides Ultrasonic imaging Womens health
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Zusammenfassung:	ObjectiveWe aimed to evaluate the association of intrahepatic triglyceride (IHTG) content in subjects with metabolically healthy abdominal obesity (MHAO) on risks of pre-diabetes plus diabetes.DesignCross-sectional survey.SettingLianqian community, the First Affiliated Hospital of Xiamen University, Xiamen, China.ParticipantsAmong 1523 community-living healthy adults aged 40 years or older with abdominal obesity recruited at baseline, 428 subjects who underwent IHTG content measurement were selected.Outcome measuresRisk of pre-diabetes plus diabetes.ResultsNon-alcoholic fatty liver disease (NAFLD) was diagnosed as 203 (69.1%) in MHAO and 121 (90.3%) in metabolically unhealthy abdominal obesity (MUAO) (p
ISSN:	2044-6055 2044-6055
DOI:	10.1136/bmjopen-2021-057820