Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020

Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be i...

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Veröffentlicht in:	Emerging infectious diseases 2020-12, Vol.26 (12), p.2974-2978
Hauptverfasser:	Hu, William T, Howell, J Christina, Ozturk, Tugba, Benameur, Karima, Bassit, Leda C, Ramonell, Richard, Cashman, Kevin S, Pirmohammed, Shama, Roback, John D, Marconi, Vincent C, Yang, Irene, Mac, Valerie V, Smith, Daniel, Sanz, Ignacio, Wharton, Whitney, Lee, F Eun-Hyung, Schinazi, Raymond F
Format:	Artikel
Sprache:	eng
Schlagworte:	2019 novel coronavirus disease Adult Aged Aged, 80 and over Antibodies Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020 Antigens Case-Control Studies coronavirus disease Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - physiopathology Disease Disease Progression Dispatch Female Georgia Health aspects Hospitalization Humans Illnesses Immune system Immunoglobulin G Immunoglobulin G - immunology Immunoglobulin M Immunoglobulin M - immunology Laboratories Male Middle Aged Pandemics Prospective Studies Proteins SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Severity of Illness Index Testing viruses
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Zusammenfassung:	Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be investigated separately from severe COVID-19.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2612.203334