Microbial differences between active and remission peri-implantitis

Peri-implantitis has a polymicrobial etiology and is a major cause of dental implant loss. Various clinical protocols for its prevention and treatment have been proposed; however, some cases show a rapid progression with non-resolving clinical symptoms. To clear a means of differentiating between such cases, the implants with peri-implantitis in this study were categorized as the active group and the remission group and that two kinds of samples were obtained from the same subjects (n = 20). The microbiome was analyzed through pyrosequencing of the 16S rRNA gene. From LEfSe results, Porphyomonas , Fusobacterium , Treponema , Tannerella, and other periodontal pathogens were abundant in the active group, while lactic acid bacteria ( Lactobacillales and Bifidobacterium ) were abundant in the remission group.