Discussion: acoustic density and ocular structures rigidity in healthy individuals and patients with primary open-angle glaucoma (response to the article by Kazemi A., Zhou B., Zhang X., Sit A.J. comparison of corneal wave speed and ocular rigidity in normal and glaucomatous eyes. J Glaucoma. 2021;30(10):932–940. DOI: 10.1097/IJG.0000000000001901)

In the first quarter of the 21st century, ideas about the pathogenesis of open-angle glaucoma (OAG) reached a new level of understanding due to the advent of modern diagnostic tools and the accumulation of a "critical mass of knowledge" in the study of key branches of its pathogenesis. However, the traditional interpretation of many clinical findings obtained in practical medicine using high-tech diagnostic equipment is often incorrect and goes against the laws of nature. This leads to gross errors in the evidence-based diagnosis. This is primarily because practitioners often lack knowledge of the manifestations of simple laws of nature in interconnected intraocular processes, which does not allow the full use of most modern diagnostic tools. Given the polarity of ideas in the world of ophthalmology regarding the theory of OAG pathogenesis, we considered it appropriate to discuss in detail the results of the present study. In our opinion, this scientific discussion will be useful not only to ophthalmologists specialized in OAG but also in other fields because it refers to understanding the physiological essence of the fundamental biomechanical characteristics of the eye and in-depth understanding of how they affect intraocular metabolism and the glaucoma process. KEYWORDS: scleral functions, rigidity, fluctuation, intraocular pressure, key branches in glaucoma pathogenesis, errors in measurement techniques, laws of mechanics. FOR CITATION: Koshits I.N., Svetlova O.V., Ryabtseva A.A., Guseva M.G., Egemberdiev M.B., Bakshinsky P.P., Zaseeva M.V. Discussion: acoustic density and ocular structures rigidity in healthy individuals and patients with primary open-angle glaucoma (response to the article by Kazemi A., Zhou B., Zhang X., Sit A.J. comparison of corneal wave speed and ocular rigidity in normal and glaucomatous eyes. J Glaucoma. 2021;30(10):932–940. DOI: 10.1097/IJG.0000000000001901). Russian Journal of Clinical Ophthalmology. 2023;23(4):231–241 (in Russ.). DOI: 10.32364/2311-7729-2023-23-4-10.