Betablockers and Ivabradine Titration According to Exercise Test in LV Only Fusion CRT Pacing

Betablockers and Ivabradine Titration According to Exercise Test in LV Only Fusion CRT Pacing

Background: Betablockers (BB)/ivabradine titration in fusion CRT pacing (CRTP) is understudied. Aim: To assess drug optimization using systematic exercise tests (ET) in fusion CRTP with preserved atrioventricular conduction (AVc). Methods: Changes in drug management were assessed during systematic f...

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Veröffentlicht in:Diagnostics (Basel) 2022-04, Vol.12 (5), p.1096
Hauptverfasser: Vacarescu, Cristina, Luca, Constantin-Tudor, Feier, Horea, Gaiță, Dan, Crișan, Simina, Negru, Alina-Gabriela, Iurciuc, Stela, Goanță, Emilia-Violeta, Mornos, Cristian, Lazăr, Mihai-Andrei, Streian, Caius-Glad, Arnăutu, Diana-Aurora, Turi, Vladiana-Romina, Cozma, Dragos
Format: Artikel
Sprache:eng
Schlagworte:
betablocker
Blood pressure
Cardiac arrhythmia
Cardiovascular disease
Drug dosages
Ergometry
exercise test
fusion CRT pacing
Heart failure
Heart rate
ivabradine optimization
Morphology
Optimization
Pacemakers
Patients
Variables
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Zusammenfassung:Background: Betablockers (BB)/ivabradine titration in fusion CRT pacing (CRTP) is understudied. Aim: To assess drug optimization using systematic exercise tests (ET) in fusion CRTP with preserved atrioventricular conduction (AVc). Methods: Changes in drug management were assessed during systematic follow-ups in CRTP patients without right ventricle lead. Shorter AVc (PR interval) allowed BB up-titration, while longer AVc needed BB down-titration, favoring ivabradine. Constant fusion pacing was the goal to improve outcomes. Results: 64 patients, 62.5 ± 9.5 y.o divided into three groups: shorter PR (
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics12051096