Extraction of Centella asiatica leaves using a mixture of subcritical dimethyl ether and ethanol: Optimization of conditions by response surface methodology

This study aimed to develop an effective extraction method to recover triterpenoid saponins from Centella asiatica (L.) Urban leaves using a mixture of subcritical dimethyl ether (DME) and ethanol (EtOH) as extractant. The optimal extraction conditions, as suggested by response surface methodology,...

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Veröffentlicht in:Wārasān Songkhlā Nakharin 2021-06, Vol.43 (3), p.711-718
Hauptverfasser: Chitaporn Pingyod, Neti Waranuch, Watoo Phrompittayarat, Panatpong Boonnoun, Kornkanok Ingkaninan
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Sprache:eng
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Zusammenfassung:This study aimed to develop an effective extraction method to recover triterpenoid saponins from Centella asiatica (L.) Urban leaves using a mixture of subcritical dimethyl ether (DME) and ethanol (EtOH) as extractant. The optimal extraction conditions, as suggested by response surface methodology, were a mixture of 2.9 ml EtOH and 5.3 g subcritical DME per g of sample at 48.7ºC. It can provide 18.8% of total triterpenoid saponins (weight/ dry weight of C. asiatica) which is 2- to 4-fold that obtained from the extractions with only EtOH (9.3%) or only subcritical DME (4.8%) under the same conditions.
ISSN:0125-3395
DOI:10.14456/sjst-psu.2021.94