Determinants of suboptimal immune recovery among a Chinese Yi ethnicity population with sustained HIV suppression

Despite sustained viral suppression with effective antiretroviral therapy (ART), HIV-infected patients with suboptimal immune recovery are still at high risk of both non-AIDS-related and AIDS-related events. The aim of this study was to investigate determinants potentially associated with suboptimal...

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Veröffentlicht in:BMC infectious diseases 2022-02, Vol.22 (1), p.137-10, Article 137
Hauptverfasser: Chen, Liyu, Liu, Chang-Hai, Kang, Shuang, Du, Lingyao, Ma, Fanghua, Li, Changmin, Bai, Lang, Li, Hong, Tang, Hong
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Sprache:eng
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Zusammenfassung:Despite sustained viral suppression with effective antiretroviral therapy (ART), HIV-infected patients with suboptimal immune recovery are still at high risk of both non-AIDS-related and AIDS-related events. The aim of this study was to investigate determinants potentially associated with suboptimal CD4 + T cell count recovery during free ART with sustained viral suppression among an HIV-infected Yi ethnicity population in Liangshan Prefecture, an area in China with high HIV prevalence. This retrospective study included HIV-infected Yi adults (≥ 18 years and baseline CD4 + T cell count less than 500 cells/μL) for whom ART supported by National Free Antiretroviral Treatment Program was initiated between January 2015 and December 2018 in Zhaojue County, Liangshan Prefecture. Virological suppression (viral load 
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-022-07113-y