CONGENITAL SELF HEALING CUTANEOUS LANGERHANS CELL HISTIOCYTOSIS WITH MULTIPLE HYPOPIGMENTED MACULES AFTER RECOVERY IN A NEONATE
Langerhans cell histiocytosis (LCH) is the most common type of childhood histiocytic disorder with an incidence of 0.2 to 1 per 100,000 children under the age of 15 years (1). The clinical picture of LCH varies from single system (S-S)bone or skin disease to multi-system disease (M-S) (2). We report...
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Veröffentlicht in: | Acta medica Iranica 2008-04, Vol.46 (1), p.84-86 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Langerhans cell histiocytosis (LCH) is the most common type of childhood histiocytic disorder with an incidence of 0.2 to 1 per 100,000 children under the age of 15 years (1). The clinical picture of LCH varies from single system (S-S)bone or skin disease to multi-system disease (M-S) (2). We report a neonate with disseminated papulonodular eruption containing mononuclear CD1a and S100 positive histiocytic cells infiltration at epidermis and underlying dermis. The diagnosis of a congenital self healing Langerhans cell histiocytosis (CSHLCH) was made and follow up showed a complete recovery of the eruptions , leaving hypopigmented macules in the sites corresponding to the initial findings. |
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ISSN: | 0044-6025 |