Assessing the association between tea intake and risk of dental caries and periodontitis: a two-sample Mendelian randomization study

Tea is an indispensable beverage in people’s daily life. However, the relationship between tea intake and dental caries and periodontitis is controversial. We extracted datasets for tea intake and oral diseases from genome-wide association studies (GWASs) conducted by the UK Biobank and the Gene Lif...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2024-02, Vol.14 (1), p.4728-9, Article 4728
Hauptverfasser:	Jin, Bilun, Chen, Heng, Liu, Peiqi, Wang, Yijie, Guo, Yi, Wang, Chenxu, Jia, Yue, Zou, Rui, Niu, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/3020/3029 692/700/3032/3086 Body mass index Dental caries Genome-wide association studies Genomes Gum disease Heterogeneity Humanities and Social Sciences multidisciplinary Oral diseases Periodontitis Pleiotropy Science Science (multidisciplinary) Single-nucleotide polymorphism Socioeconomic factors Socioeconomics Tea Teeth
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Tea is an indispensable beverage in people’s daily life. However, the relationship between tea intake and dental caries and periodontitis is controversial. We extracted datasets for tea intake and oral diseases from genome-wide association studies (GWASs) conducted by the UK Biobank and the Gene Lifestyle Interactions in Dental Endpoints consortium. We selected 38 single-nucleotide polymorphisms (SNPs) significantly associated with tea intake as instrumental variables (IVs) ( P
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-024-54860-w