SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia

(1) that serum collected from malaria-infected persons in Cambodia before the coronavirus disease (COVID-19) pandemic harbored seroreactivity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens but lacked neutralizing activity. To test this hypothesis, we analyzed 237 dried...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2022-05, Vol.28 (5), p.1080-1081
Hauptverfasser:	Grassia, Jillian T, Markwalter, Christine F, O'Meara, Wendy P, Taylor, Steve M, Obala, Andrew A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral Cambodia - epidemiology coronavirus disease Coronaviruses COVID-19 Cross Reactions cross-reactivity Disease transmission Erythrocytes Humans Hypotheses Infections Letter Malaria neutralizing antibodies Plasmodium falciparum SARS-CoV-2 SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia Severe acute respiratory syndrome coronavirus 2
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	(1) that serum collected from malaria-infected persons in Cambodia before the coronavirus disease (COVID-19) pandemic harbored seroreactivity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens but lacked neutralizing activity. To test this hypothesis, we analyzed 237 dried blood spot samples taken in January 2020 (prepandemic) from P. falciparum–exposed persons in a high-transmission setting in western Kenya for the presence of SARS-CoV-2 neutralizing antibodies (nAbs) using the GenScript SARS-CoV2 sVNT assay (https://www.genscript.com). Impact of asymptomatic Plasmodium falciparum infection on the risk of subsequent symptomatic malaria in a longitudinal cohort in Kenya. eLife. 2021;10:e68812 .
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2805.220404