Efficacy of topiramate as add-on therapy in two different types of progressive myoclonic epilepsy

The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora's disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with mark...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove 2013, Vol.56 (1), p.36-38
Hauptverfasser:	Demir, Caner Feyzi, Ozdemir, Hasan Hüseyin, Müngen, Bülent
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - therapeutic use Drug Therapy, Combination Female Fructose - analogs & derivatives Fructose - therapeutic use Humans Myoclonic Epilepsies, Progressive - drug therapy Progressive myoclonic epilepsy Topiramate Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora's disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with marked decrease in myoclonic seizure frequency and improvement of quality of life. Topiramate appears to be a useful alternative agent in cases of PME and could be consider for adjunctive therapy.
ISSN:	1211-4286 1805-9694
DOI:	10.14712/18059694.2014.37