Primary results of replacement the experimental hyaline cartilage defect with human fibroblast cell culture

The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a cons...

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Veröffentlicht in:Vestnik medit͡s︡inskogo instituta Reaviz 2022-05, Vol.12 (2), p.14-21
Hauptverfasser: Bozhokin, M. S., Marchenko, D. M., Mikhailova, E. R., Antipov, A. P., Nashchekina, Yu. A., Vcherashnij, D. B., Novoseltsev, S. V., Kruglov, V. N.
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Sprache:eng
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Zusammenfassung:The hyaline cartilage damage problem is actual, but existing recovery methods are not fully sufficient. A promising solution of this problem can be the implantation of a tissue-engineered structure (TEC), consisting of a cell culture and a biodegradable scaffold. In this experiment we created a construct consisting of a polylactide scaffold and a human dermal fibroblasts culture. After implantation of TEC in the modeled defect area we analyzed the experimental group regeneration results in comparison to the control group.
ISSN:2226-762X
2782-1579
DOI:10.20340/vmi-rvz.2022.2.MORPH.1