Difficulties in choosing antibacterial therapy regimen for nosocomial pneumonia in intensive care units: clinical observations

Nosocomial pneumonia is one of the most common healthcare-associated infections and the most frequent in intensive care unit (ICU) patients. The clinical and economic consequences of nosocomial pneumonia are very significant, especially for ventilated patients. In this article we present several clinical observations that demonstrate the difficulties of antibacterial therapy of nosocomial pneumonia and ventilator-associated pneumonia in adults in multidisciplinary hospitals in Moscow, which are due to both patient characteristics and profile of circulating pathogens.