Model of the Impact of Focused Ultrasound on Biological Tissues

To study tissue permeability under extracorporeal exposure to various types of radiation, it is necessary to use multiphysical and mathematical modeling of all stages of the technology being developed, taking into account the dielectric and acoustic properties of human body tissues. The technologies used in medicine with focused ultrasound often have a high level of artifacts in the visualization of diagnostic studies and complications during therapy. When modeling exposure to focused ultrasound, the applied solvers must take into account pressure wave propagation, density changes and jumps, non-linearity and diffusion losses that occur in human tissues, and offer simulation of acoustic propagation in inhomogeneous installations in near real time. The article presents the results of multiphysics and mathematical modeling in the Sim4Life for Science V7.0 package using a full-wave acoustic solver (P-ACOUSTICS) of modern computational acoustics.