Comparative study between the analgesic effect of ketorolac when administrated intravenous preoperatively versus when added to local anesthesia in squint surgery

This study aimed to investigate the safety and the analgesic and anesthetic efficacy of preoperative intravenous ketorolac as well as combined ketorolac with local anesthesia (LA) for peribulbar block. This trial enrolled adults scheduled for strabismus surgery under peribulbar block who were allocated into three groups (n = 30). The control group (C) received LA mixture containing lidocaine (2%, 10 ml) and hyaluronidase (5 IU/ml). The ketorolac group (K) received ketorolac (30 mg, intravenously) 30 minutes before LA injection. The ketorolac local group (KL) received an LA mixture to which ketorolac (4 mg/ml) was added. The onset of anesthesia was significantly shorter in the KL group than in the K group (39.3 ± 6.9 versus 58.5 ± 13.4 sec, p