Effectiveness of shengxuexiaoban capsules combined with glucocorticoid therapy for immune thrombocytopenia: A meta-analysis

Effectiveness of shengxuexiaoban capsules combined with glucocorticoid therapy for immune thrombocytopenia: A meta-analysis

ObjectiveTo evaluate the effectiveness of the Shengxuexiaoban Capsules combined with glucocorticoid therapy for immune thrombocytopenia (ITP).MethodsWe collected randomized controlled trials (RCTs) using shengxuexiaoban capsules in combination with glucocorticoid to treat ITP by searching major Chin...

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Veröffentlicht in:PloS one 2022-09, Vol.17 (9), p.e0275122
Hauptverfasser: Meng-Yuan Ding, Bing Li, Meng Yang, Wen-Sheng Zhai, Chun-Dong Song, Jian Zhang, Qiu-Yue Zhang, Peng-Fei Li, Li-Ya Liu
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Sprache:eng
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Zusammenfassung:ObjectiveTo evaluate the effectiveness of the Shengxuexiaoban Capsules combined with glucocorticoid therapy for immune thrombocytopenia (ITP).MethodsWe collected randomized controlled trials (RCTs) using shengxuexiaoban capsules in combination with glucocorticoid to treat ITP by searching major Chinese and English electronic databases. The outcome indicators were the effective rate, recurrence rate, the number of platelets in the blood, recovery time of platelets, and adverse reactions. We used STATA 16.0 and RevMan 5.3 for meta-analysis and GRADE pro. for evidence quality evaluation.ResultsA total of 27 RCTs were included in the meta-analysis, and the results showed a significant difference (all p
ISSN:1932-6203
DOI:10.1371/journal.pone.0275122