Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis

The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease. Nineteen MSG male mice were divided into HBOT treated and control groups at 12 weeks of ages. The HBOT group was treated...

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Veröffentlicht in:	TheScientificWorld 2011-01, Vol.2011 (2011), p.1-12
Hauptverfasser:	Chen, Shao-Yuan, Aburada, Masaki, Iizuka, Seiichi, Shimada, Tsutomu, Suzuki, Wataru, Sasaki, Yoshiyuki, Fujimoto, Makoto, Chen, Yen-Chen, Tsuneyama, Koichi, Nagata, Mitsunobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Care and treatment Fatty Liver - complications Fatty Liver - therapy Health aspects Hepatitis Hyperbaric Oxygenation Hyperlipidemia Hyperlipidemias - blood Hyperlipidemias - complications Hyperlipidemias - therapy Immunohistochemistry Intra-Abdominal Fat - pathology Liver - pathology Male Mice Obesity Obesity - complications Obesity - therapy Oxygen Physiological aspects Tumor Necrosis Factor-alpha - metabolism
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Zusammenfassung:	The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease. Nineteen MSG male mice were divided into HBOT treated and control groups at 12 weeks of ages. The HBOT group was treated with hyperbaric oxygen from 12 to 14 weeks (first phase) and then from 16 to 18 weeks (second phase). Interestingly, the body weight of the HBOT group was significantly lower (P
ISSN:	2356-6140 1537-744X 1537-744X
DOI:	10.1100/2011/380236