Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore

Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case-control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, an...

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Veröffentlicht in:	Emerging infectious diseases 2018-08, Vol.24 (8), p.1565-1568
Hauptverfasser:	Yan, Gabriel, Pang, Long, Cook, Alex R, Ho, Hanley J, Win, Mar Soe, Khoo, Ai Leng, Wong, Joshua G X, Lee, Chun Kiat, Yan, Benedict, Jureen, Roland, Ho, Siew Seen, Lye, David C, Tambyah, Paul A, Leo, Yee Sin, Fisher, Dale, Oon, Jolene, Bagdasarian, Natasha, Chow, Angela, Smitasin, Nares, Chai, Louis Yi Ann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aedes - virology Aged Animals Case-Control Studies Cohort Studies Conjunctivitis Conjunctivitis, Viral - diagnosis Conjunctivitis, Viral - physiopathology Conjunctivitis, Viral - virology Dengue - diagnosis Dengue - physiopathology Dengue - transmission Dengue - virology Dengue Virus Diagnosis, Differential Dispatch Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore Female Fever - diagnosis Fever - physiopathology Fever - virology Health aspects Health care industry Humans Infection Leukocyte Count Male Medical research Middle Aged Mosquito Vectors - virology Myalgia - diagnosis Myalgia - physiopathology Myalgia - virology Platelet Count platelets ROC Curve Singapore Southeast Asia viruses Zika Virus Zika Virus Infection - diagnosis Zika Virus Infection - physiopathology Zika Virus Infection - transmission Zika Virus Infection - virology
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Beschreibung
Zusammenfassung:	Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case-control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2408.171883