High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders

IntroductionStudies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system.AimThis study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule wi...

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Veröffentlicht in:PloS one 2020-01, Vol.15 (9), p.e0238044
Hauptverfasser: Talita M Fernandes, Enrico F Puggina, Celso T Mendes-Junior, Milena C de Paula, Paulin Sonon, Eduardo A Donadi, Ana Paula M Fernandes
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Sprache:eng
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Zusammenfassung:IntroductionStudies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system.AimThis study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule with the fat mass and muscle mass index among 77 bodybuilders and 64 controls.ResultsThe comparisons of the percentage of body fat (%BF) revealed that the groups of male and female bodybuilders showed a statistically significant reduction in the percentage of body fat when compared to their control group, (P
ISSN:1932-6203
DOI:10.1371/journal.pone.0238044