Difficulties of Mobilization and Harvesting of Hematopoietic Stem Cells in Heavily Pre-Treated Patients

This study presents a new method of combined growth factor mobilization with increased dose (15 μg/kg) of filgrastim and standard mono dose of plerixafor in subjects with multiple myeloma, Hodgkin or non-Hodgkin lymphoma. Efficient mobilization is a key factor in the treatment of this group of patie...

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Veröffentlicht in:Journal of Interdisciplinary Medicine 2017-03, Vol.2 (1), p.41-44
Hauptverfasser: Lázár, Erzsébet, Köpeczi, Judit-Beáta, Kakucs, Enikő, Benedek, István, Jakab, Szende, Pakucs, Annamária, Tudor, Cezara
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Sprache:eng
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Zusammenfassung:This study presents a new method of combined growth factor mobilization with increased dose (15 μg/kg) of filgrastim and standard mono dose of plerixafor in subjects with multiple myeloma, Hodgkin or non-Hodgkin lymphoma. Efficient mobilization is a key factor in the treatment of this group of patients, because autologous transplantation can be performed in cases in which we succeed to obtain a minimally sufficient number of stem cells. Autologous stem cell transplantation is included in the current standard treatment of multiple myeloma and in the relapsed cases of lymphomas.
ISSN:2501-8132
2501-8132
DOI:10.1515/jim-2017-0028