Hydrogen bonding in push-pull 5-substituted-2-alkylidene-4-oxothiazolidines: 1H-MNR spectroscopic study

Application of dynamic 1H-NMR spectroscopy added to the understanding of the hydrogen bonds existing in the structurally related 5-substituted-2-alkylidene-4-oxothiazolidines in polar and apolar solvents. The equilibrated mixtures of these typical push-pull alkenes in CDCl3 consist of the intramolecularly H-bonded (E)-isomer and intermolecularly H-bonded (Z)-isomer in varying proportions which depend on the solvent polarity. For the representative of the series (Z)-2-(5-ethoxycarbonylmethyl-4-oxothiazolidin-2-ylidene)-1-phenylethanone a concentration effect on the degree of intermolecular hydrogen bonding in apolar CDCl3 has been studied. Primenom dinamicke 1H-NMR spektroskopije doslo se do boljeg razumevanja o vrsti vodonicnih veza koje postoje u strukturno slicnim 5-supstituisanim 2-alkiliden-4-oksotiazolidinima u polarnim i apolarnim rastvaracima. Uravnotezene smese ovih tipicnih push-pull alkena u CDCl3 sadrze (E)-izomer vezan intramolekulskom vodonicnom vezom kao i intermolekulski vodonicnom vezom vezan (Z)-izomer u razlicitim odnosima, koji zavise od polarnosti rastvaraca. U slucaju tipicnog predstavnika serije (Z)-2-(5-etoksikarbonilmetil-4-oksotiazolidin- 2-iliden)-1-feniletanona uticaj koncentracije na stepen stvaranja intermolekulske vodonicne veze u apolarnom CDCl3 je takodje proucavan.