Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series

Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases o...

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Veröffentlicht in:	Journal of asthma and allergy 2021-01, Vol.14, p.241-244
Hauptverfasser:	Nucera, Eleonora, Urbani, Sara, Buonomo, Alessandro, De Pasquale, Tiziana, Rizzi, Angela, Aruanno, Arianna, Pucci, Stefano
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic reaction Allergies Allergy Anaphylaxis Asthma Case Series Contrast agents Contrast media Gadolinium gadolinium-based contrast agents Histamine hypersensitivity ige-mediated reactions Immunoglobulin E Immunology Magnetic resonance imaging Surface active agents Urticaria
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Zusammenfassung:	Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
ISSN:	1178-6965 1178-6965
DOI:	10.2147/JAA.S295748