Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation

Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis). We describe the case of a 48 years-old woman with axonal neuropathy associated with prot...

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Veröffentlicht in:Arquivos de neuro-psiquiatria 2004-09, Vol.62 (3A), p.725-729
Hauptverfasser: Barsottini, Orlando G Povoas, Arantes, Adriano, Sigulem, Daniel, Kutner, José Mauro, Ribeiro, Andreza Alice Feitosa, Moura, Luiz A, Hamerschlak, Nelson
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Sprache:eng
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Zusammenfassung:Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis). We describe the case of a 48 years-old woman with axonal neuropathy associated with proteinuria, whose final investigation resulted in diagnosis of primary amyloidosis (AL). She was submitted to autologous bone marrow transplantation. We discuss some aspects related to diagnosis of neuropathy and current treatment of AL.
ISSN:0004-282X
1678-4227
0004-282X
1678-4227
DOI:10.1590/S0004-282X2004000400030