Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules

Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules

In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β-catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes e...

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Veröffentlicht in:International Journal of Endocrinology 2013-01, Vol.2013 (2013), p.90-100-011
Hauptverfasser: Chojnacka, Katarzyna, Hejmej, Anna, Bilinska, Barbara, Lydka-Zarzycka, Marta, Kuras, Paulina, Kotula-Balak, Malgorzata
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Animals
Bisphenol A
Endocrinology
Ethanol
Light
Males
Membrane proteins
Physiological aspects
Proteins
Solvents
Spermatogenesis
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Zusammenfassung:In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β-catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and distribution of N-cadherin, β-catenin, and Cx43 were photoperiod dependent. Long-term treatment with OP (200 mg/kg b.w.) resulted in the reduction of junction proteins expressions (P
ISSN:1687-8337
1687-8345
DOI:10.1155/2013/134589