PROFILE OF ANTICANCER ACTIVITIES OF BROTOWALI (Tinospora crispa L.) PLANTS OFVARIOUS REGIONS IN EAST JAWA

PROFILE OF ANTICANCER ACTIVITIES OF BROTOWALI (Tinospora crispa L.) PLANTS OFVARIOUS REGIONS IN EAST JAWA

Brotowali (Tinosporacrispa L) is a plant which has potential to be a chemopreventive agent. This study aims to determine the profile of anticancer activity of brotowali stem extracts (Tinosporacrispa L.), from several regions in East Java. The extraction was carried out by maceration method using 80...

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Veröffentlicht in:Jurnal farmasi sains dan komunitas (Online) 2020-02, Vol.16 (2), p.68-77
Hauptverfasser: Mutiah, Roihatul, Azizah, Laily Nurul, Annisa, Rahmi, Listyana, Anik
Format: Artikel
Sprache:eng
Schlagworte:
anticancer profile
brotowali (tinospora crispa l.)
east java
microtetrazolium (mtt) assay method
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Zusammenfassung:Brotowali (Tinosporacrispa L) is a plant which has potential to be a chemopreventive agent. This study aims to determine the profile of anticancer activity of brotowali stem extracts (Tinosporacrispa L.), from several regions in East Java. The extraction was carried out by maceration method using 80% ethanol solvent. Then, anticancer activity test was carried out on MCF-7 breast cancer cell model using the Microtetrazolium (MTT) Assay method. The results of the anticancer activity test showed that 15 brotowali stem extracts taken from 5 locations in East Java had significant differences in anticancer activity (P
ISSN:1693-5683
2527-7146
DOI:10.24071/jpsc.002020